常山乙素，Febrifugine

图片 常山乙素，Febrifugine
别名：3-[3-[(2R,3S)-3-羟基-2-哌啶基]-2-氧代丙基]-4(3H)-喹唑啉酮；双色胺 B；β-二色红；3-[3-[(2R,3S)-3-Hydroxy-2-piperidinyl]-2-oxopropyl]-4(3H)-quinazolinone; (+)-Febrifugine; Dichroin B; NSC 315535; trans-(+)-Febrifugine; β-Dichroin; β-Dichroine
制造商品牌: 加拿大TRC
货号（SKU）: F229020
CAS号: 24159-07-7
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Product Description

Catalogue NumberF229020
Chemical NameFebrifugine
Synonyms3-[3-[(2R,3S)-3-Hydroxy-2-piperidinyl]-2-oxopropyl]-4(3H)-quinazolinone; (+)-Febrifugine; Dichroin B; NSC 315535; trans-(+)-Febrifugine; β-Dichroin; β-Dichroine
CAS Number24159-07-7
Molecular Formula：C16H19N3O3
Molecular Weight301.34
CategoryStandards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsFebrifugine is a quinazoline alkaloid with significant antimalarial and anticancerous efficacy. Febrifugine is an NRF2 inhibitor, that works with halofuginone for the treatment of chemo- and radio-resistant forms of cancer. Febrifugine analogs also functions as antimalarial, anticancer agents and in the prevention of chicken coccidiosis.
ReferencesPandey, R. K., et al.: J. Biomol. Struct. Dyn., 35, 791 (2017); Tsuchida, K., et al.: Free Radic. Biol. Med., 103, 236 (2017); Doan T. M., et al.: Tetrahedron Lett., 55, 7226 (2014); Guo, Z., et al.: Zhongguo Shouyi Xuebao, 35, 1382 (2015)
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储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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