| Catalogue Number | C475503 |
| Chemical Name | Cinobufotalin |
| Synonyms | (3β,5β,15β,16β)-16-(Acetyloxy)-14,15-epoxy-3,5-dihydroxybufa-20,22-dienolide; 14,15-Epoxy-14H-cyclopenta[a]phenanthrene, bufa-20,22-dienolide deriv.; NSC 90326; 14,15β-Epoxy-3β,5,16β-trihydroxy-5β-bufa-20,22-dienolide 16-Acetate |
| CAS Number | 1108-68-5 |
| Molecular Formula | C26H34O7 |
| Appearance | White to Off-White Solid |
| Melting Point | 253-256°C |
| Molecular Weight | 458.54 |
| Storage | -20°C Freezer |
| Solubility | Chloroform (Slightly), DMSO (Slightly, Sonicated), Methanol (Slightly) |
| Category | Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; |
| Applications | Cinobufotalin is used in combination with irinotecan and capecitabine for treating advanced colorectal cancer, study of the clinical curative effect in the treatment of cancer pain, pre-clinical evaluation of cinobufotalin as potential anti-lung cancer agent. |
| | Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package |
| References | Qian, M., et al.: Chongqing Yixue, 44, 3112 (2015); Yu, B., et al.: Xiandai Zhongxiyi Jiehe Zazhi, 24, 3997 (2015); Kai, S., et al.: Biochem. Biophys. Res. Commun., 452, 768 (2014) |
