依西美坦，Exemestane；≥98% (HPLC)

图片 依西美坦，Exemestane；≥98% (HPLC)
别名：6-亚甲基-雄-1,4-二烯-3,17-二酮；6-Methyleneandrosta-1,4-diene-3,17-dione

Empirical Formula (Hill Notation): C20H24O2 CAS号: 107868-30-4 分子量: 296.40 MDL编号: MFCD00866994 PubChem化学物质编号: 329823675 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: PZ0006
CAS号: 107868-30-4
MDL号: MFCD00866994
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说明

生化/生理作用

Exemestane is a steroidal antiestrogen and irreversible aromatase inhibitor. Exemestane acts as a false substrate for the aromatase enzyme. Exemestane also prevents the conversion of androgens to estrogens and is used to treat estrogen-dependent breast cancer.
 

特点和优势

This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
 

其他说明

This compound was developed by Pfizer for Cytokines & Growth Factors research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.
To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
 

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.
 
 

属性

质量水平

100

检测方案

≥98% (HPLC)

形式

powder

旋光性

[α]/D +250 to +300°, c = 1 in methanol

manufacturer/tradename

Pfizer®

颜色

white to off-white

溶解性

DMSO: ≥20 mg/mL

创始人

Pfizer

储存温度

2-8°C

SMILES string

C[C@]12CC[C@H]3[C@@H](CC(=C)C4=CC(=O)C=C[C@]34C)[C@@H]1CCC2=O

InChI

1S/C20H24O2/c1-12-10-14-15-4-5-18(22)20(15,3)9-7-16(14)19(2)8-6-13(21)11-17(12)19/h6,8,11,14-16H,1,4-5,7,9-10H2,2-3H3/t14-,15-,16-,19+,20-/m0/s1

InChI key

BFYIZQONLCFLEV-DAELLWKTSA-N

Gene Information

human ... CYP19A1(1588)

 

安全信息

象形图

Health hazardEnvironment
GHS08,GHS09

警示用语：

Danger

危险声明

H360 - H411

危险分类

Aquatic Chronic 2 - Repr. 1B

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.2-8°C冷藏
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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