伊维菌素B1a-D2，Ivermectin B1a-D2

图片 伊维菌素B1a-D2，Ivermectin B1a-D2
别名：伊维菌素-d2；5-O-去甲基-22,23-二氢阿维菌素A1a-D2；2,23-二氢阿维菌素B1a-D2；二氢阿维菌素 B1a-D2；5-O-Demethyl-22,23-dihydro-avermectin A1a-D2; 2,23-Dihydroavermectin B1a-D2; Dihydroavermectin B1a-D2
制造商品牌: 加拿大TRC
货号（SKU）: I940817
CAS号: 71827-03-7
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Product Description

Catalogue NumberI940817
Chemical NameIvermectin B1a-D2
Synonyms5-O-Demethyl-22,23-dihydro-avermectin A1a-D2; 2,23-Dihydroavermectin B1a-D2; Dihydroavermectin B1a-D2;
Alternate CAS #Unlabelled: 71827-03-7
Molecular FormulaC₄₈H₇₂D₂O₁₄
AppearancePale Beige to Brown Solid
Melting Point>150°C (dec.)
Molecular Weight877.11
Storage-20°C, Inert atmosphere
SolubilityDMSO (Slightly), Methanol (Slightly)
CategoryStandards; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsIvermectin B1a-D2 is a deuterium labelled analogue of Ivermectin B1a (I940815), which is a major component of Ivermectin (I940800), a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). An invitro inhibitor of SARS-CoV-2/ Covid-19.
ReferencesChabala, J.C., et al.: J. Med. Chem., 23, 1134 (1980); Campbell, W.C., et al.: Science, 221, 823 (1983); Bennett, J.L., et al.: Parasitol. Today, 4, 226 (1988); Plaisier, A.P., et al.: J. Infect. Dis., 172, 204 (1995);; Caly, L., et al.: Antivir. Res., 178
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属性名称属性值
储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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