舒罗培南 [硫培南]，Sulopenem；≥98% (HPLC)

图片 舒罗培南 [硫培南]，Sulopenem；≥98% (HPLC)
别名：(5R,6S)-6-(1R)-1-羟乙基-7-氧代-3-(1R,3S)-四氢-1-氧化-3-噻吩硫基-4-硫杂-1-氮杂双环3.2.0庚-2-烯-2-羧酸；CP-70429；(5R,6S)-6-(1R)-1-Hydroxyethyl-7-oxo-3-(1R,3S)-tetrahydro-1-oxido-3-thienylthio-4-thia-1-azabicyclo3.2.0hept-2-ene-2-carboxylic acid

Empirical Formula (Hill Notation): C12H15NO5S3 CAS号: 120788-07-0 分子量: 349.45 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: PZ0042
CAS号: 120788-07-0
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¥1,756.00

说明

生化/生理作用

Sulopenem is an orally available penem antibiotic designed to treat Gram-negative multi-drug resistant infections. It can be administered as an intravenous preparation, and it is also orally available.
Sulopenem, formerly CP-70,429, is stable to renal dehydropeptidase I and hydrolytic activity of AmpC β-lactamases and extended-spectrum β-lactamases (ESBLs) that convey resistance to third-generation cephalosporins. This action of sulopenem helps to act against urgent drug-resistant antimicrobial threats, including ESBL-producing Enterobacteriaceae.[1] Sulopenem is effective than ciprofloxacin for treating urogenital upper urinary tract infection (uUTI) in adult women due to quinolone non-susceptible pathogens.[2]
 

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.
 
 

属性

测定

≥98% (HPLC)

形式

powder

mfr. no.

Pfizer®

颜色

white to beige

溶解性

DMSO: 2 mg/mL, clear

创始人

Pfizer

运输

dry ice

储存温度

−20°C

SMILES string

O=C(O)C1=C(SC@@H2CS@+(O-)CC2)SC@@3(H)N1C(C@3(H)C@H(O)C)=O

InChI

1S/C12H15NO5S3/c1-5(14)7-9(15)13-8(11(16)17)12(20-10(7)13)19-6-2-3-21(18)4-6/h5-7,10,14H,2-4H2,1H3,(H,16,17)/t5-,6?,7+,10-,21?/m1/s1

InChI key

FLSUCZWOEMTFAQ-JNCILSLHSA-N

 

安全信息

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

商品规格
属性名称属性值
储存温度 Storage temp.-20°C低温冷冻
全球实时库存 Availability √美国St. Louis ≥ 20 | 欧洲Eur. ≥ 16 | 東京Tokyo ≥ 5 | 香港与北京 ≥ 20
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