PF-06273340，≥98% (HPLC)

图片 PF-06273340，≥98% (HPLC)
别名：N-(5-{2-Amino-7-(2-hydroxy-1 ,1-dimethylethyl)-7H-pyrrolo2,3-dpyrimidin-5- ylcarbonyl}pyridin-3-yl)-2-(5-chloropyridin-2-yl)acetamide, PF 06273340, N-5-2-Amino-7-(2-hydroxy-1,1-dimethylethyl)-7H-pyrrolo2,3-dpyrimidin-5-ylcarbonyl-3-pyridinyl-5-chloro-2-pyridineacetamide, PF06273340

Empirical Formula (Hill Notation): C23H22ClN7O3 CAS号: 1402438-74-7 分子量: 479.92 PubChem化学物质编号: 329823793 NACRES: NA.77
制造商品牌: 西格玛 Sigma-Aldrich
货号（SKU）: PZ0254
CAS号: 1402438-74-7
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¥1,391.58

说明

生化/生理作用

PF-06273340 is a brain penetrant, orally available and potent tropomyosin-related kinase (Trk) inhibitor. PF-06273340 is under development as a remedy acute and chronic pain.
 

其他说明

This compound was developed by Pfizer for Cytokines & Growth Factors research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.
To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
 

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.
 
 

属性

质量水平

100

测定

≥98% (HPLC)

形式

powder

mfr. no.

Pfizer®

颜色

, white to yellow to brown

溶解性

DMSO: 20 mg/mL, clear

创始人

Pfizer

储存温度

room temp

SMILES string

CC(CO)(C)N1C2=NC(N)=NC=C2C(C(C3=CN=CC(NC(CC4=CC=C(Cl)C=N4)=O)=C3)=O)=C1

InChI

1S/C23H22ClN7O3/c1-23(2,12-32)31-11-18(17-10-28-22(25)30-21(17)31)20(34)13-5-16(9-26-7-13)29-19(33)6-15-4-3-14(24)8-27-15/h3-5,7-11,32H,6,12H2,1-2H3,(H,29,33)(H2,25,28,30)

InChI key

BPIWZDNVMQQBQX-UHFFFAOYSA-N

 

安全信息

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H302

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

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